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Revue Marocaine de Medecine et Sante. 2004; 21 (2): 25-30
in French | IMEMR | ID: emr-68282

ABSTRACT

Because the serology keep's a place in the diagnosis of hydatid cyst of lung with radiology, different techniques are used: Complement fixation technique; electrosyneresis, agglutination, indirect immunofluorescence, Elisa, Immunoblot assay. However, their specificity and their sensitivity are not identical, and can lead to discordant results. In this study, we have compared the serological techniques results with surgical results. 44 patients were tested between 63, observed in pneumology service during 4 years [1997-2000]. For the sensitivity, Elisa[IgG] and immunofluorescence are positive in 23 patients [65%], and negative in 12 patients [34%] [the doorstep of sensitivity for Elisa[IgG] is fixed from DO=0.3]. The Elisa[IgA] is positive in 12 patients [34%], and negative in 23 patients [65%] [The doorstep of sensitivity is fixed from DO=0.2]. The electrosyneresis is positive in 16 patients [46%], and negative in 19 patients [54%]. We have the same results with literature knowing that in hydatid cyst of lung the sensitivity is low. For specificite, only Elisa[IgG] has a false positivity in two case: Thymoma and carcinoma with a low level [400-200]. This results show that the serological techniques keep's their place for the diagnosis of hydatid cyst of lung in spite of the lack of sensitivity and specificity. This lack can be compensed by using Immunoblot assay


Subject(s)
Humans , Male , Female , Serologic Tests , Serology , Enzyme-Linked Immunosorbent Assay , Fluorescent Antibody Technique, Indirect , Immunodiffusion , Immunoglobulin A , Immunoglobulin G
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